ACY1 Antibody

ACY1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to take part in the catabolism and salvage of acylated amino acids. Defects in ACY1 are the source of aminoacylase-1 deficiency (ACY1D). ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. Epileptic seizures are a frequent feature.

Catalog Number: AS-P00081

Lead time: 3-4 business days

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Products specifications

Applications	ACY1 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.
Synonyms	ACY1D, ACYLASE, ACY-1, EC 3.5.1.143.
Reagent Appearance	Sterile filtered colorless solution.
Type	Mouse Anti Human Monoclonal.
Clone	PAT1E2AT.
Immunogen	Anti-human ACY1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ACY1 amino acids 1-408 purified from E. coli.
Ig Subclass	Mouse IgG2b heavy chain and ? light chain.
Purification Method	ACY1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Protein formulation	1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Storage Procedures	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life	12 months at -20°C. 1 month at 4°C.