ADAMTS1 Antibody

Catalog Number: ASA-B0036
Lead time: 1 week
$299.00

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

ADAM metallopeptidase with thrombospondin type 1 motif, 1 Polyclonal IgG Rabbit Mouse, Rat WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of mouse ADAMTS1(956-968aa KHYIDFCTLTQCS), different from the related rat sequence by one amino acid, and from the related human sequence by four amino acids.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 ml sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

ADAMTS1

Protein

A disintegrin and metalloproteinase with thrombospondin motifs 1

Uniprot ID

P97857

Function

Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. Has angiogenic inhibitor activity (By similarity). Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture (By similarity).

Tissue Specificity

 

Sub-cellular localization

Secreted, extracellular space, extracellular matrix.

Sequence Similarities

Contains 1 disintegrin domain.

Aliases

A disintegrin and metalloproteinase with thrombospondin motifs 1 antibody|A disintegrin like and metalloprotease with thrombospondin type 1 motif 1 antibody|A disintegrin-like and metalloprotease(reprolysin type) with thrombospondin type 1 motif 1 antibody|ADAM metallopeptidase with thrombospondin type 1 motif 1 antibody|ADAM TS 1 antibody|ADAM TS1 antibody|ADAM-TS 1 antibody|ADAM-TS1 antibody|ADAMTS 1 antibody|ADAMTS antibody|ADAMTS-1 antibody|Adamts1 antibody|ATS1_HUMAN antibody|C3 C5 antibody|KIAA1346 antibody|KIAA1346, antibody|METH 1 antibody|METH-1 antibody|METH1 antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Rat Mouse AssaySolution's ECL kit


AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information

Anti-ADAMTS1 antibody, ASA-B0036, Western blotting
Lane 1: Rat Liver Tissue Lysate
Lane 2: Rat Heart Tissue Lysate
Lane 3: Rat Brain Tissue Lysate