ADAMTS5 Antibody

Catalog Number: ASA-B0039

Lead time: 1 week

$299.00

Qty:

Overview

Long Name	Antibody Type	Antibody Isotype	Host	Species Reactivity	Validated Applications	Purification
ADAM metallopeptidase with thrombospondin type 1 motif, 5	Polyclonal	IgG	Rabbit	Human, Mouse, Rat	IHC-P, WB	Immunogen affinity purified.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS5(772-787aa TAYLALKKKNGEYLIN), different from the related mouse and rat sequence by one amino acid.

Properties

Form	Lyophilized
Size	100 µg/vial
Contents	Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.
Concentration	Reconstitute with 0.2 ml sterile dH2O (500 µg/ml final concentration).
Storage	At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene	ADAMTS5
Protein	A disintegrin and metalloproteinase with thrombospondin motifs 5
Uniprot ID	Q9UNA0
Function	Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.
Tissue Specificity	Expressed at low level in placenta primarily but also detected in heart and brain, cervix, uterus, bladder, esophagus, rib cartilage, chondroblastoma, fibrous tissue and a joint capsule from an arthritic patient.
Sub-cellular localization	Secreted, extracellular space, extracellular matrix .
Sequence Similarities	Contains 1 disintegrin domain.
Aliases	A disintegrin and metalloproteinase with thrombospondin motifs 11 antibody\|A disintegrin and metalloproteinase with thrombospondin motifs 5 antibody\|A disintegrin like and metalloprotease(reprolysin type) with thrombospondin type 1 motif 5 antibody\|A disintegrin like and metalloprotease(reprolysin type) with thrombospondin type 1 motif, 5(aggrecanase 2) antibody\|A Disintigrin And Metalloproteinase with ThromboSpondin motif-5 antibody\|ADAM metallopeptidase with thrombospondin type 1 motif 5 antibody\|ADAM TS 11 antibody\|ADAM TS 5 antibody\|ADAM TS5 antibody\|ADAM-TS 11 antibody\|ADAM-TS 5 antibody\|ADAM-TS5 antibody\|ADAMTS 11 antibody\|ADAMTS 5 antibody\|ADAMTS-11 antibody\|ADAMTS-5 antibody\|ADAMTS11 antibody\|Adamts5 antibody\|ADMP 2 antibody\|ADMP-2 antibody\|ADMP2 antibody\|Aggrecanase 2 antibody\|Aggrecanase-2 antibody\|ATS5_HUMAN antibody\|FLJ36738 antibody\|Implantin antibody\|ThromboSpondin motif-5 antibody

Application Details

Application	Concentration*	Species	Validated Using**
Western blot	0.1-0.5μg/ml	Human, Rat Mouse	AssaySolution's ECL kit
Immunohistochemistry(Paraffin-embedded Section)	0.5-1μg/ml	Rat Human, Mouse	AssaySolution's IHC/ICC Detection kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information

Anti-ADAMTS5 antibody, ASA-B0039, IHC(P)
Rat Brain Tissue

Anti-ADAMTS5 antibody, ASA-B0039, Western blotting
All lanes: Anti ADAMTS5 (ASA-B0039) at 0.5ug/ml
Lane 1: Rat Heart Tissue Lysate at 50ug
Lane 2: HELA Whole Cell Lysate at 40ug
Lane 3: COLO320 Whole Cell Lysate at 40ug
Lane 4: MCF-7 Whole Cell Lysate at 40ug
Lane 5: A549 Whole Cell Lysate at 40ug
Predicted bind size: 102KD
Observed bind size: 102KD

Anti-ADAMTS5 antibody, ASA-B0039, IHC(P)
Rat Brain Tissue

ADAMTS5 Antibody

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification

Immunogen

Properties

Form

Size

Contents

Concentration

Storage

Additional Information Regarding the Antigen

Gene

Protein

Uniprot ID

Function

Tissue Specificity

Sub-cellular localization

Sequence Similarities

Aliases

Application Details