Newsletter

5HT3A receptor Antibody

Catalog Number: ASA-B0009
Lead time: 1 week
$260.00

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

5-hydroxytryptamine(serotonin) receptor 3A, ionotropic Polyclonal IgG Rabbit Human IHC-P, WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human5HT3A receptor(140-154aa RHQGEVQNYKPLQVV).

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 ml sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

HTR3A

Protein

5-hydroxytryptamine receptor 3A(5-HT3-A/5-HT3A)

Uniprot ID

P46098

Function

This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.

Tissue Specificity

Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta.

Sub-cellular localization

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Sequence Similarities

 

Aliases

5 HT 3 antibody|5 HT3 receptor antibody|5 HT3A antibody|5 HT3A receptor antibody|5 HT3R antibody|5 HT3RA antibody|5 hydroxytryptamine(serotonin) receptor 3A antibody|5-HT-3 antibody|5-HT3-A antibody|5-HT3A antibody|5-HT3R antibody|5-hydroxytryptamine receptor 3 antibody|5-hydroxytryptamine receptor 3A antibody|5HT 3 antibody|5HT 3A antibody|5HT receptor antibody|5HT3 serotonin receptor antibody|5HT3A_HUMAN antibody|5HT3R antibody|HTR3 antibody|Htr3a antibody|Serotonin gated ion channel receptor antibody|Serotonin receptor 3A antibody|Serotonin-gated ion channel receptor 3a antibody|Serotonin-gated ion channel receptor antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Human AssaySolution's ECL kit
Immunohistochemistry(Paraffin-embedded Section) 0.5-1μg/ml Human AssaySolution's IHC/ICC Detection kit


AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information

Anti-5HT3A receptor antibody, ASA-B0009, Western blotting
Lane 1: U87 Cell Lysate
Lane 2: HELA Cell Lysate
Lane 3: SW620 Cell Lysate
 
 
 
 
 
 
 
Assay Solution's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.