ABCA4 Antibody

Catalog Number: ASA-B0014
Lead time: 1 week


Long Name

Antibody Type

Antibody Isotype


Species Reactivity

Validated Applications


ATP-binding cassette, sub-family A(ABC1), member 4 Polyclonal IgG Rabbit Mouse, Rat WB Immunogen affinity purified.


A synthetic peptide corresponding to a sequence at the C-terminus of mouse ABCA4(1892-1903aa TLLIQHHFFLTR), identical to the related rat sequence.





100 µg/vial


Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.


Reconstitute with 0.2 ml sterile dH2O (500 µg/ml final concentration).


At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen




Retinal-specific ATP-binding cassette transporter

Uniprot ID



In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans- retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery (By similarity).

Tissue Specificity

Retinal-specific. Seems to be exclusively found in the rims of rod photoreceptor cells.

Sub-cellular localization

Membrane ; Multi-pass membrane protein . Note: Localized to outer segment disk edges of rods and cones, with around one million copies/photoreceptor.

Sequence Similarities

Belongs to the ABC transporter superfamily. ABCA family.


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Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Mouse Rat AssaySolution's ECL kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information

Anti-ABCA4 antibody, ASA-B0014, Western blotting
All lanes: Anti ABCA4 (ASA-B0014) at 0.5ug/ml
WB: Mouse Brain Tissue Lysate at 50ug
Predicted bind size: 256KD
Observed bind size: 256KD
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