ABCB6 Antibody

Catalog Number: ASA-B0019
Lead time: 1 week
$260.00

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

ATP-binding cassette, sub-family B(MDR/TAP), member 6 Polyclonal IgG Rabbit Human IHC-P, ICC, WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human ABCB6(818-842aa YADMWQLQQGQEETSEDTKPQTMER).

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 ml sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

ABCB6

Protein

ATP-binding cassette sub-family B member 6, mitochondrial

Uniprot ID

Q9NP58

Function

Binds heme and porphyrins and functions in their ATP- dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.

Tissue Specificity

Widely expressed. High expression is detected in the retinal epithelium.

Sub-cellular localization

Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. Endosome . Note: localized to the endosome- like compartement and dendrite tips.

Sequence Similarities

Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.

Aliases

ABC antibody|ABC transporter umat antibody|ABC14 antibody|Abcb6 antibody|ABCB6_HUMAN antibody|ATP binding cassette sub family B member 6, mitochondrial precursor antibody|ATP binding cassette, sub family B(MDR/TAP), member 6 antibody|ATP-binding cassette sub-family B member 6 antibody|Mitochondrial ABC transporter 3 antibody|mitochondrial antibody|Mt ABC transporter 3 antibody|Mt-ABC transporter 3 antibody|MTABC3 antibody|P glycoprotein related protein antibody|P-glycoprotein-related protein antibody|PRP antibody|Ubiquitously expressed mammalian ABC half transporter antibody|Ubiquitously-expressed mammalian ABC half transporter antibody|UMAT antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Human AssaySolution's ECL kit
Immunohistochemistry(Paraffin-embedded Section) 0.5-1μg/ml Human AssaySolution's IHC/ICC Detection kit
Immunocytochemistry 0.5-1μg/ml Human AssaySolution's IHC/ICC Detection kit


AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P) and ICC. *Blocking peptide can be purchased at $65. Contact us for more information

Anti-ABCB6 antibody, ASA-B0019, Western blotting
All lanes: Anti ABCB6 (ASA-B0019) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: MCF-7 Whole Cell Lysate at 40ug
Lane 3: A549 Whole Cell Lysate at 40ug
Predicted band size: 94KD
Observed band size: 94KD
 
Anti-ABCB6 antibody, ASA-B0019, IHC(P)
Human Mammary Cancer Tissue
 
 
 
 
Assay Solution's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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