ABI2 Antibody

Catalog Number: ASA-B0024
Lead time: 1 week
$260.00

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

abl-interactor 2 Polyclonal IgG Rabbit Human, Mouse, Rat WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human ABI2(158-173aa RFKVSTQNMKMGGLPR), identical to the related mouse and rat sequences.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 ml sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

ABI2

Protein

Abl interactor 2

Uniprot ID

Q9NYB9

Function

May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA.

Tissue Specificity

 

Sub-cellular localization

Cytoplasm .

Sequence Similarities

Belongs to the ABI family.

Aliases

Abelson interactor 2 antibody|ABI 2 antibody|ABI2B antibody|Abl binding protein 3 antibody|Abl interacting protein 1(SH3 containing protein) antibody|Abl interactor 2 antibody|Abl interactor protein 2b antibody|AblBP3 antibody|AIP 1 antibody|Arg binding protein 1 antibody|Arg protein tyrosine kinase binding protein antibody|ArgBP1 antibody|ARGBPIA antibody|ArgBPIB antibody|OTTHUMP00000163783 antibody|OTTHUMP00000163784 antibody|OTTHUMP00000206182 antibody|OTTHUMP00000206183 antibody|OTTHUMP00000206184 antibody|OTTHUMP00000206185 antibody|SSH3BP2 antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Human, Rat Mouse AssaySolution's ECL kit


AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information

Anti-ABI2 antibody, ASA-B0024, Western blotting
Lane 1: Rat Brain Tissue Lysate
Lane 2: Human Placenta Tissue Lysate
Lane 3: MCF-7 Cell Lysate
Lane 4: HELA Cell Lysate
Lane 5: JURKAT Cell Lysate
 
 
 
 
 
 
 
Assay Solution's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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