ADAM19 Antibody

Catalog Number: ASA-B0034
Lead time: 1 week
$260.00

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

ADAM metallopeptidase domain 19 Polyclonal IgG Rabbit Human, Mouse, Rat IHC-P, WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human ADAM19(286-298aa RRKLLAQKYHDNA), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 ml sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

ADAM19

Protein

Disintegrin and metalloproteinase domain-containing protein 19

Uniprot ID

Q9H013

Function

Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity).

Tissue Specificity

Expressed in many normal organ tissues and several cancer cell lines.

Sub-cellular localization

Membrane; Single-pass type I membrane protein.

Sequence Similarities

Contains 1 disintegrin domain.

Aliases

A disintegrin and metalloproteinase domain 19(meltrin beta) antibody|A disintegrin and metalloproteinase domain 19 antibody|ADAM 19 antibody|ADAM metallopeptidase domain 19 antibody|Disintegrin and metalloproteinase domain containing protein 19 antibody|FKSG 34 antibody|FKSG34 antibody|MADDAM antibody|Meltrin beta antibody|Metalloprotease and disintegrin dentritic antigen marker antibody|MLTN B antibody|MLTNB antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Human, Rat Mouse AssaySolution's ECL kit
Immunohistochemistry(Paraffin-embedded Section) 0.5-1μg/ml Human, Rat Mouse AssaySolution's IHC/ICC Detection kit


AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information

Anti-ADAM19 antibody, ASA-B0034, Western blotting
Lane 1: Rat Spleen Tissue Lysate
Lane 2: Rat Intestine Tissue Lysate
Lane 3: Rat Brain Tissue Lysate
Lane 4: HELA Cell Lysate
 
Anti-ADAM19 antibody, ASA-B0034, IHC(P)
Rat Spleen Tissue
 
Anti-ADAM19 antibody, ASA-B0034, IHC(P)
Human Lung Cancer Tissue
 
Assay Solution's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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