ADAMTS2 Antibody

Catalog Number: ASA-B0037
Lead time: 1 week
$260.00

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

ADAM metallopeptidase with thrombospondin type 1 motif, 2 Polyclonal IgG Rabbit Human, Mouse, Rat IHC-P, IHC-F, WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS2(1189-1204aa KTRNQRIQELIDEMRK), different from the related rat and mouse sequences by three amino acids.

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 ml sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

ADAMTS2

Protein

A disintegrin and metalloproteinase with thrombospondin motifs 2(ADAM-TS 2/ADAM-TS2/ADAMTS-2)

Uniprot ID

O95450

Function

Cleaves the propeptides of type I and II collagen prior to fibril assembly. Does not act on type III collagen. May also play a role in development that is independent of its role in collagen biosynthesis.

Tissue Specificity

Expressed at high level in skin, bone, tendon and aorta and at low levels in thymus and brain.

Sub-cellular localization

Secreted, extracellular space, extracellular matrix .

Sequence Similarities

Contains 1 disintegrin domain.

Aliases

A disintegrin and metalloproteinase with thrombospondin motifs 2 antibody|A disintegrin like and metalloprotease(reprolysin type) with thrombospondin type 1 motif 2 antibody|ADAM metallopeptidase with thrombospondin type 1 motif 2 antibody|ADAM TS 2 antibody|ADAM TS2 antibody|ADAM-TS 2 antibody|ADAM-TS2 antibody|ADAMTS 3 antibody|ADAMTS-2 antibody|ADAMTS2 antibody|ATS2_HUMAN antibody|EC 3.4.24.14 antibody|EDS VIIB antibody|EDS VIIC antibody|hPCPNI antibody|NPI antibody|PC I NP antibody|PC I-NP antibody|PCINP antibody|PCPNI antibody|pNPI antibody|Procollagen I N proteinase antibody|Procollagen I N-proteinase antibody|Procollagen I/II amino propeptide processing enzyme antibody|Procollagen I/II amino propeptide-processing enzyme antibody|Procollagen N endopeptidase antibody|Procollagen N-endopeptidase antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Human, Rat Mouse AssaySolution's ECL kit
Immunohistochemistry(Paraffin-embedded Section) 0.5-1μg/ml Human, Rat Mouse AssaySolution's IHC/ICC Detection kit
Immunohistochemistry(Frozen Section) 0.5-1μg/ml Rat Human, Mouse AssaySolution's IHC/ICC Detection kit


AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P) and IHC(F). *Blocking peptide can be purchased at $65. Contact us for more information

Anti-ADAMTS2 antibody, ASA-B0037, Western blotting
Lane 1: Rat Brain Tissue Lysate
Lane 2: Rat Heart Tissue Lysate
 
Anti-ADAMTS2 antibody, ASA-B0037, IHC(P)
Rat Cardiac Muscle Tissue
 
Anti-ADAMTS2 antibody, ASA-B0037, IHC(F)
Rat Cardiac Muscle Tissue
 
Assay Solution's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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