Canine Neuropilin-1 ELISA Kit

Catalog Number: AYQ-E10282
Lead time: 3-4 business days
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$0.00
Products specifications
Background Neuropilin is a protein receptor active in neurons.There are two forms of Neuropilins, NRP-1 and NRP-2. They are transmembrane glycoproteins, and predominantly co-receptors for another class of proteins known as semaphorins. Of the semaphorins, NRP-1 and NRP-2 are specifically receptors for class-3 semaphorins, which, among many things, are responsible for axon guidance during the development of the nervous system in vertebrates.Neuropilins work as co-receptors as they have a very small cytoplasmic domain and thus rely upon other molecules (normally plexins) to transduce their signals across a cell membrane. Neuropilins generally work as dimers and different combinations have different affinities for molecules. For example, NRP-1 homodimers have high affinity for Sema3A, whilst NRP-2 homodimers have high affinity for Sema3F. Another ligand for neuropilins is VEGF, a growth factor involved in the regulation of angiogenesis.
Typical Data ELISA: Canine Neuropilin-1 ELISA Kit (Colorimetric) These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
Applications ELISA
Sample Volume 50-100ul
Suitable Sample Type serum, plasma, tissue homogenates, cell lysate, cell culture medium.
Assay Type Sandwich ELISA
Intra Assay CV%<8%
Inter Assay CV%<10%
Sensitivity 25 pg/ml
Standard Curve Range 31.3--2000 pg/ml
Notes Please contact our Technical Services with any questions regarding species reactivity
Kit Components Assay plate (12 x 8 coated Microwells), Standard (Freeze dried), Biotin-antibody (60 x concentrate), HRP-avidin (20 x concentrate), Biotin-antibody Diluent, HRP-avidin Diluent, Sample Diluent, Wash Buffer (20 x concentrate), TMB Substrate, Stop Solution, Adhesive Strip (For 96 wells), Instruction manual
Specificity This assay has high sensitivity and excellent specificity for detection Canine Neuropilin-1. No significant cross-reactivity or Canine Neuropilin-1 and analogues was observed.
Species canine
Synonym BDCA4; BDCA-4; CD304 antigen; CD304; DKFZp686A03134; DKFZp781F1414; neuropilin 1; Neuropilin1; Neuropilin-1; NRP1; NRPNP1; transmembrane receptor; Vascular endothelial cell growth factor 165 receptor; VEGF165RCD304
Gene Symbol BDCA4
Gene ID 477955
Storage Store the unopened product at 2 - 8° C. Protect from light. Do not use past expiration date.
Assay Solution's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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