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ELISA
Ultrasensitive Detection iPCR Kit
Bone Biomarkers
Cardiac Biomarkers
Tumor Biomarkers
ImmunoMetabolism Biomarkers
Assay Kits
Magnetic beads
Magnetic beads for protein/antibody and DNA purification, immunoprecipitation, CHIP assay
The Excel table for antibody affinity comparison
Antibodies
Immunohistochemistry (IHC) - Premier
Immunohistochemistry (IHC)
Secondary Antibodies
Flow Cytometry
Conjugated Antibodies
Unconjugated Antibodies
Isotype Control Antibodies
Western Blot
Matched Antibody Pairs
Human
Mouse
Rat
Swine
Chicken
Protein
Magnetic Beads
Proteins and Peptides
Services
Support
Catalogs
Articles
Immunohistochemistry (IHC)
Immunometabolism Biomarkers
Blood Coagulation and Anemia Biomarkers
Bone Biomarkers
Cardiac Biomarkers
Tumor Biomarkers
Promotion Events
Contact
Categories
ELISA
Assay Kits
Magnetic beads
Antibodies
Immunohistochemistry (IHC) - Premier
Immunohistochemistry (IHC)
Secondary Antibodies
Flow Cytometry
Western Blot
Matched Antibody Pairs
Protein
Services
Support
Promotion Events
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Immunohistochemistry (IHC) - Premier
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CD44 (Premier)
CD44 (Premier)
Size: 100 µL
Catalog Number:
ASA-S1057
$
325.00
Qty:
Product Attachments
CD44 Datasheet.pdf
Products specifications
Description
Cluster of differentiation 44 (CD44) is a glycoprotein receptor for hyaluronic acid, which plays a fundamental role in cellular adhesion, stromal binding, migration, and cell-cell interactions. Studies have suggested that the CD44-hyaluronate interaction is central to tumor invasiveness. Positive staining with Anti-CD44 is implicated in a multitude of different cancer types, including breast, prostatic, renal cell, colonic, hepatocellular, and genitourinary carcinomas, as well as Non-Hodgkin’s Lymphoma, metastatic melanoma, gastric cancer, and some soft tissue tumors. It has also been demonstrated that there is a positive correlation between tumor progression and increased expression of CD44v, a high molecular weight CD44 isoform that has been described in epithelial cells. Given the expression of CD44 in a wide range of cancers, the most practical application of CD44 immunostaining is its use in discriminating between urothelial transitional cell carcinoma in situ from non-neoplastic changes in the urothelium.
Source
Mouse Monoclonal
Positive Control
Benign Urothelium
Dilution Range
1:100 - 1:200
Assay Solution's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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