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ELISA
Ultrasensitive Detection iPCR Kit
Bone Biomarkers
Cardiac Biomarkers
Tumor Biomarkers
ImmunoMetabolism Biomarkers
Assay Kits
Magnetic beads
Magnetic beads for protein/antibody and DNA purification, immunoprecipitation, CHIP assay
The Excel table for antibody affinity comparison
Antibodies
Immunohistochemistry (IHC) - Premier
Immunohistochemistry (IHC)
Secondary Antibodies
Flow Cytometry
Conjugated Antibodies
Unconjugated Antibodies
Isotype Control Antibodies
Western Blot
Matched Antibody Pairs
Human
Mouse
Rat
Swine
Chicken
Protein
Magnetic Beads
Proteins and Peptides
Services
Support
Catalogs
Articles
Immunohistochemistry (IHC)
Immunometabolism Biomarkers
Blood Coagulation and Anemia Biomarkers
Bone Biomarkers
Cardiac Biomarkers
Tumor Biomarkers
Promotion Events
Contact
Categories
ELISA
Assay Kits
Magnetic beads
Antibodies
Immunohistochemistry (IHC) - Premier
Immunohistochemistry (IHC)
Secondary Antibodies
Flow Cytometry
Western Blot
Matched Antibody Pairs
Protein
Services
Support
Promotion Events
Contact
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Immunohistochemistry (IHC) - Premier
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PD-L1 (Premier)
PD-L1 (Premier)
Size: 100 µL
Catalog Number:
ASA-S1025
$
340.00
Qty:
Product Attachments
PSA-Datasheet
Products specifications
Description
Programmed Death-Ligand 1 (PD-L1), also known as CD274 or B7 Homolog 1 (B7-H1), is a transmembrane protein involved in suppressing the immune system and rendering tumor cells resistant to CD8+ T cell-mediated lysis through binding of the Programmed Death-1 (PD-1) receptor. Overexpression of PD-L1 may allow cancer cells to evade the actions of the host immune system. In renal cell carcinoma, upregulation of PD-L1 has been linked to increased tumor aggressiveness and risk of death, and, in ovarian cancer, higher expression of this protein has lead to significantly poorer prognosis. PD-L1 has also been linked to systemic lupus erythematosus and cutaneous melanoma. When considered in adjunct with CD8+ tumor-infiltrating lymphocyte density, expression levels of PD-L1 may be a useful predictor of multiple cancer types, including stage III non-small cell lung cancer, hormone receptor negative breast cancer, and sentinel lymph node melanoma.
Source
Rabbit Monoclonal
Positive Control
Tonsil, Lung Adenocarcinoma
Dilution Range
1:100 - 1:200
Assay Solution's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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