Gene
|
HTR3A |
Protein
|
5-hydroxytryptamine receptor 3A(5-HT3-A/5-HT3A) |
Uniprot ID
|
P46098 |
Function
|
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel. |
Tissue Specificity
|
Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. |
Sub-cellular localization
|
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Sequence Similarities
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Aliases
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5 HT 3 antibody|5 HT3 receptor antibody|5 HT3A antibody|5 HT3A receptor antibody|5 HT3R antibody|5 HT3RA antibody|5 hydroxytryptamine(serotonin) receptor 3A antibody|5-HT-3 antibody|5-HT3-A antibody|5-HT3A antibody|5-HT3R antibody|5-hydroxytryptamine receptor 3 antibody|5-hydroxytryptamine receptor 3A antibody|5HT 3 antibody|5HT 3A antibody|5HT receptor antibody|5HT3 serotonin receptor antibody|5HT3A_HUMAN antibody|5HT3R antibody|HTR3 antibody|Htr3a antibody|Serotonin gated ion channel receptor antibody|Serotonin receptor 3A antibody|Serotonin-gated ion channel receptor 3a antibody|Serotonin-gated ion channel receptor antibody |