Activin-A Antibody

Activins are homodimers or heterodimers of the different β subunit isoforms, part of the TGFβ family. Mature Activin A has two 116 amino acids residues βA subunits (βA-βA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.

Catalog Number: AS-P00070

Lead time: 3-4 business days

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Products specifications

Solubility	Add 0.1 ml of distilled water and let the lyophilized pellet dissolve completely.
Applications	Activin-A antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. In order to detect Human Activin A by indirect ELISA a dilution of at least 1:1,000 of the Activin A antibody is required. Activin A antibody, in conjunction with compatible secondary reagents (anti rabbit AP conjugated), allows the detection of 0.2-1 ng /well of Human Activin A. In order to detect human Activin A by WB analysis this IgG can be used in a dilution of 1:1,000.
Synonyms	Inhba, Inhibin beta A, FSH releasing protein.
Reagent Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Type	Polyclonal Rabbit Antibody.
Immunogen	Recombinant human Activin-A produced in plants.
Purification Method	Purified IgG prepared by affinity chromatography on protein G.
Protein formulation	Lyophilized from a sterile filtered (0.2um) solution containing phosphate buffered saline.