ADAM2 Antibody

Catalog Number: ASA-B0035
Lead time: 1 week
$299.00

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification 

ADAM metallopeptidase domain 2 Polyclonal IgG Rabbit Human WB Immunogen affinity purified.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human ADAM2(701-715aa VLIAIMVKVNFQRKK).

Properties

Form

Lyophilized

Size

100 µg/vial

Contents

Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.

Concentration

Reconstitute with 0.2 ml sterile dH2O (500 µg/ml final concentration).

Storage

At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene

ADAM2

Protein

Disintegrin and metalloproteinase domain-containing protein 2

Uniprot ID

Q99965

Function

Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.

Tissue Specificity

Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.

Sub-cellular localization

Membrane; Single-pass type I membrane protein.

Sequence Similarities

Contains 1 disintegrin domain.

Aliases

A disintegrin and metalloproteinase domain 2 antibody|ADAM 2 antibody|ADAM metallopeptidase domain 2 antibody|Adam2 antibody|ADAM2_HUMAN antibody|AI323749 antibody|Cancer/testis antigen 15 antibody|CRYN1 antibody|CRYN2 antibody|CT15 antibody|Disintegrin and metalloproteinase domain-containing protein 2 antibody|Fertilin beta antibody|Fertilin subunit beta antibody|Ftnb antibody|PH 30 antibody|PH 30b antibody|PH-30 antibody|PH30 antibody|Ph30 beta antibody|PH30-beta antibody

Application Details

Application Concentration* Species Validated Using**
Western blot 0.1-0.5μg/ml Human AssaySolution's ECL kit


AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information

Anti-ADAM2 antibody, ASA-B0035, Western blotting
SMMC Cell Lysate