ADAMTS4 Antibody

Catalog Number: ASA-B0038

Lead time: 1 week

$299.00

Qty:

Overview

Long Name	Antibody Type	Antibody Isotype	Host	Species Reactivity	Validated Applications	Purification
ADAM metallopeptidase with thrombospondin type 1 motif, 4	Polyclonal	IgG	Rabbit	Human, Mouse, Rat	WB	Immunogen affinity purified.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS4(820-837aa RRAQILEILRRRPWAGRK), different from the related rat and mouse sequences by three amino acids.

Properties

Form	Lyophilized
Size	100 µg/vial
Contents	Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request.
Concentration	Reconstitute with 0.2 ml sterile dH2O (500 µg/ml final concentration).
Storage	At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene	ADAMTS4
Protein	A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAM-TS 4/ADAM-TS4/ADAMTS-4)
Uniprot ID	O75173
Function	Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-
Tissue Specificity	Expressed in brain, lung and heart. Expressed at very low level in placenta and skeletal muscles. Isoform 2 is detected in osteoarthritic synovium.
Sub-cellular localization	Secreted, extracellular space, extracellular matrix .
Sequence Similarities	Contains 1 disintegrin domain.
Aliases	A disintegrin and metalloproteinase with thrombospondin motifs 4 antibody\|A disintegrin like and metalloprotease(reprolysin type) with thrombospondin type 1 motif 4 antibody\|A disintegrin like and metalloprotease with thrombospondin type 1 motif 4 antibody\|ADAM metallopeptidase with thrombospondin type 1 motif 4 antibody\|ADAM TS 4 antibody\|ADAM TS4 antibody\|ADAM-TS 4 antibody\|ADAM-TS4 antibody\|ADAMTS 2 antibody\|ADAMTS 4 antibody\|ADAMTS-4 antibody\|ADAMTS2 antibody\|ADAMTS4 antibody\|ADAMTS4 protein antibody\|ADMP 1 antibody\|ADMP-1 antibody\|ADMP1 antibody\|Aggrecanase 1 antibody\|Aggrecanase-1 antibody\|Aggrecanase1 antibody\|ATS4_HUMAN antibody\|KIAA0688 antibody

Application Details

Application	Concentration*	Species	Validated Using**
Western blot	0.1-0.5μg/ml	Human, Mouse, Rat	AssaySolution's ECL kit

AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information

Anti-ADAMTS4 antibody, ASA-B0038, Western blotting
Lane 1: Rat Brain Tissue Lysate
Lane 2: Mouse Brain Tissue Lysate

ADAMTS4 Antibody

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification

Immunogen

Properties

Form

Size

Contents

Concentration

Storage

Additional Information Regarding the Antigen

Gene

Protein

Uniprot ID

Function

Tissue Specificity

Sub-cellular localization

Sequence Similarities

Aliases

Application Details