Cathepsin D Antibody (monoclonal)

Catalog Number: ASA-B0311

Lead time: 1 week

$299.00

Qty:

Overview

Long Name	Antibody Type	Antibody Isotype	Host	Species Reactivity	Validated Applications	Purification
cathepsin D	Monoclonal	IgG	Mouse	Human	IHC-P, WB	Ascites
Immunogen
Human liver cathepsin D.

Properties

Form	Lyophilized
Size	100 µg/vial
Contents	Mouse ascites fluid, 1.2% sodium acetate, 2 mg BSA, with 0.01 mg NaN3 as preservative. *carrier free antibody available upon request.
Concentration	1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100 µg/ml.
Storage	At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing.

Additional Information Regarding the Antigen

Gene	CTSD
Protein	Cathepsin D
Uniprot ID	Human(P07339), Mouse(P18242), Rat(P24268)
Function	Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Tissue Specificity	Expressed in the aorta extrcellular space (at protein level).
Sub-cellular localization	Lysosome. Melanosome. Secreted, extracellular space. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380).
Sequence Similarities	Belongs to the peptidase A1 family.
Aliases	CLN10\|CPSD\|cathepsin D(lysosomal aspartyl protease)\|ceroid-lipofuscinosis, neuronal 10

Application Details

Application	Concentration*	Species	Validated Using**
Western blot	0.5-1μg/ml	Human	AssaySolution's ECL kit
Immunohistochemistry(Paraffin-embedded Section)	1-2μg/ml	Human	AssaySolution's IHC/ICC Detection kit

AssaySolution recommends Mouse Chemiluminescent WB Detection Kit (AKIT003B) for Western blot, and Mouse Peroxidase IHC/ICC Detection Kit (AKIT004B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information

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Cathepsin D Antibody (monoclonal)

Overview

Long Name

Antibody Type

Antibody Isotype

Host

Species Reactivity

Validated Applications

Purification

Immunogen

Properties

Form

Size

Contents

Concentration

Storage

Additional Information Regarding the Antigen

Gene

Protein

Uniprot ID

Function

Tissue Specificity

Sub-cellular localization

Sequence Similarities

Aliases

Application Details