ZNF346 Human

ZNF346 is a nucleolar, zinc finger protein which specially binds to double-stranded RNA or RNA/DNA fusions, instead of DNA alone. Zinc finger domains vital for dsRNA binding and essential for its nucleolar localization. ZNF346 takes part in cell growth and survival.

Catalog Number: AS-P06009

Lead time: 3-4 business days

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ZNF346 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 317 amino acids (1-294) and having a molecular mass of 35.3 kDa.ZNF346 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Products specifications

Expression host	Escherichia Coli.
Purity	Greater than 90.0% as determined by SDS-PAGE.
Formulation	The ASCC1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT.
Synonyms	Zinc finger protein 346, JAZ, Zfp346, ZNF346.
Reagent Appearance	Sterile Filtered colorless solution.
Stability	Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino acid sequence	MGSSHHHHHH SSGLVPRGSH MGSMEYPAPA TVQAADGGAA GPYSSSELLE GQEPDGVRFD RERARRLWEA VSGAQPVGRE EVEHMIQKNQ CLFTNTQCKV CCALLISESQ KLAHYQSKKH ANKVKRYLAI HGMETLKGET KKLDSDQKSS RSKDKNQCCP ICNMTFSSPV VAQSHYLGKT HAKNLKLKQQ STKVEALHQN REMIDPDKFC SLCHATFNDP VMAQQHYVGK KHRKQETKLK LMARYGRLAD PAVTDFPAGK GYPCKTCKIV LNSIEQYQAH VSGFKHKNQS PKTVASSLGQ IPMQRQPIQK DSTTLED.